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Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Frontiers of Medicine 2021, Volume 15, Issue 4,   Pages 638-643 doi: 10.1007/s11684-021-0831-z

Abstract: The COVID-19 pandemic has caused numerous deaths around the world. A growing body of evidence points to the important role of overwhelming inflammatory responses in the pathogenesis of COVID-19 and the effectiveness of anti-inflammation therapy against COVID-19 is emerging. In addition to affecting the lungs, COVID-19 can be a severe systemic inflammatory disease that is related to endothelial dysfunction. We are calling for closer attention to endothelial dysfunction in COVID-19 not only for fully revealing the pathogenic mechanism of COVID-19 but also for properly adjusting the strategy of clinical intervention.

Keywords： COVID-19     endothelial dysfunction     inflammation reaction     cytokine stor<strong>mstrong>    

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<strong>Mercury removal from aqueous solution using petal-like MoSstrong><strong>2strong><strong> nanosheetsstrong>

Ragini Pirarath, Palani Shivashanmugam, Asad Syed, Abdallah M.

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 1, doi: 10.1007/s11783-020-1307-0

Abstract: Abstract • Synthesized few-layered MoS2 nanosheets via surfactant-assisted hydrothermal method. • Synthesized MoS2 nanosheets show petal-like morphology. • Adsorbent showed 93% of mercury removal efficiency. • The adsorption of mercury is attributed to negative zeta potential (-21.8 mV). Recently, different nanomaterial-based adsorbents have received greater attention for the removal of environmental pollutants, specifically heavy metals from aqueous media. In this work, we synthesized few-layered MoS2 nanosheets via a surfactant-assisted hydrothermal method and utilized them as an efficient adsorbent for the removal of mercury from aqueous media. The synthesized MoS2 nanosheets showed petal-like morphology as confirmed by scanning electron microscope and high-resolution transmission electron microscopic analysis. The average thickness of the nanosheets is found to be about 57 nm. Possessing high stability and negative zeta potential makes this material suitable for efficient adsorption of mercury from aqueous media. The adsorption efficiency of the adsorbent was investigated as a function of pH, contact time and adsorbent dose. The kinetics of adsorption and reusability potential of the adsorbent were also performed. A pseudo-second-order kinetics for mercury adsorption was observed. As prepared MoS2 nanosheets showed 93% mercury removal efficiency, whereas regenerated adsorbent showed 91% and 79% removal efficiency in the respective 2nd and 3rd cycles. The adsorption capacity of the adsorbent was found to be 289 mg/g at room temperature.

Keywords： Anionic surfactant     2D material     MoS2 nanosheets     Mercury removal     Adsorption capacity    

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<strong>FESEstrong><strong>’s Best Papers of 2017strong>

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 3, doi: 10.1007/s11783-018-1051-x

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<strong>Photosynthesis and related metabolic mechanism of promoted rice (strong><strong>Oryza sativastrong><strong> L.) growth by TiOstrong><strong>2strong><strong> nanoparticlesstrong>

Yingdan Zhang, Na Liu, Wei Wang, Jianteng Sun, Lizhong Zhu

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 6, doi: 10.1007/s11783-020-1282-5

Abstract: Abstract • The rice growth was promoted by nano-TiO2 of 0.1–100 mg/L. • Nano-TiO2 enhanced the energy storage in photosynthesis. • Nano-TiO2 reduced energy consumption in carbohydrate metabolism and TCA cycle. Titanium dioxide nanoparticle (nano-TiO2), as an excellent UV absorbent and photo-catalyst, has been widely applied in modern industry, thus inevitably discharged into environment. We proposed that nano-TiO2 in soil can promote crop yield through photosynthetic and metabolic disturbance, therefore, we investigated the effects of nano-TiO2 exposure on related physiologic-biochemical properties of rice (Oryza sativa L.). Results showed that rice biomass was increased >30% at every applied dosage (0.1–100 mg/L) of nano-TiO2. The actual photosynthetic rate (Y(II)) significantly increased by 10.0% and 17.2% in the treatments of 10 and 100 mg/L respectively, indicating an increased energy production from photosynthesis. Besides, non-photochemical quenching (Y(NPQ)) significantly decreased by 19.8%–26.0% of the control in all treatments respectively, representing a decline in heat dissipation. Detailed metabolism fingerprinting further revealed that a fortified transformation of monosaccharides (D-fructose, D-galactose, and D-talose) to disaccharides (D-cellobiose, and D-lactose) was accompanied with a weakened citric acid cycle, confirming the decrease of energy consumption in metabolism. All these results elucidated that nano-TiO2 promoted rice growth through the upregulation of energy storage in photosynthesis and the downregulation of energy consumption in metabolism. This study provides a mechanistic understanding of the stress-response hormesis of rice after exposure to nano-TiO2, and provides worthy information on the potential application and risk of nanomaterials in agricultural production.

Keywords： Nano-TiO2     Rice     Photosynthesis     Metabolomics     Energy storage    

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<strong>Adsorption characteristics of ciprofloxacin onto g-MoSstrong><strong>2strong><strong> coated biochar nanocompositesstrong>

Zhenyu Yang, Rong Xing, Wenjun Zhou, Lizhong Zhu

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 3, doi: 10.1007/s11783-019-1218-0

Abstract: In addition, the adsorption of CIP onto g-MoS2-BC composites also exhibited strong dependence on the

Keywords： Adsorption     Ciprofloxacin     g-MoS2 nanosheets     Biochar     Soil remediation    

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<strong>A newly defined dioxygenase system from strong><strong>Mycobacterium vanbaaleniistrong><strong> PYR-1 endowed with an enhanced activity of dihydroxylation of high-molecular-weight polyaromatichydrocarbonsstrong>

Yiquan Wu, Ying Xu, Ningyi Zhou

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 1, doi: 10.1007/s11783-019-1193-5

Abstract: The Km, kcat, kcat/Km values of the PhtAd were 123±26.9 M, 503±49.9 min−1, 4.1 M−1·min−1, respectivelyAnd the Km, kcat, kcat/Km values of the ferredoxin PhtAc were 52.5±9.7 M, 3.8±0.19 min−1 and 0.07 M−1

Keywords： Biodegradation     polyaromatic hydrocarbons     biotransformation     ring-hydroxylating dioxygenase system    

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<strong>Fabrication and photocatalytic ability of an Au/TiOstrong><strong>2strong><strong>/reduced graphene oxide nanocompositestrong>

Fenghe Lv, Hua Wang, Zhangliang Li, Qi Zhang, Xuan Liu, Yan Su

Frontiers of Environmental Science & Engineering 2018, Volume 12, Issue 1, doi: 10.1007/s11783-017-0977-8

Abstract: A new type of Au/TiO /reduced graphene oxide (RGO) nanocomposite was fabricated by the hydrothermal synthesis of TiO on graphene oxide followed by the photodeposition of Au nanoparticles. Transmission electron microscopy images showed that Au nanoparticles were loaded onto the surface of both TiO and RGO. Au/TiO /RGO had a better photocatalytic activity than Au/TiO for the degradation of phenol. Electrochemical measurements indicated that Au/TiO /RGO had an improved charge transfer capability. Meanwhile, chemiluminescent analysis and electron spin resonance spectroscopy revealed that Au/TiO /RGO displayed high production of hydrogen peroxide and hydroxyl radicals in the photocatalytic process. This high photocatalytic performance was achieved via the addition of RGO in Au/TiO /RGO, where RGO served not only as a catalyst support to provide more sites for the deposition of Au nanoparticles but also as a collector to accept electrons from TiO to effectively reduce photogenerated charge recombination.

Keywords： Reduced graphene oxide     Au     TiO2     Nanocomposite     Photocatalysis    

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<strong>Effects of cultivation strategies on the cultivation of strong><strong>Chlorellastrong><strong> sp.HQ in photoreactorsstrong>

Xiaoya Liu, Yu Hong, Peirui Liu, Jingjing Zhan, Ran Yan

Frontiers of Environmental Science & Engineering 2019, Volume 13, Issue 5, doi: 10.1007/s11783-019-1162-z

Abstract: Heterotrophic cultivation caused high level of ROS and high lipids accumulation. HMTC is the best culture strategy for improving the microalgal biomass. Chlorella sp. HQ had great nutrient removal capacity under five culture strategies. The effects of cultivation strategies (including autotrophic cultivation (AC), heterotrophic cultivation (HC), fed-batch cultivation (FC), heterotrophic+ autotrophic two-stage cultivation (HATC), and heterotrophic+ mixotrophic two-stage cultivation (HMTC)) on the growth and lipid accumulation of Chlorella sp. HQ and its total nitrogen (TN) and total phosphorus (TP) removal in secondary effluent were investigated in column photoreactors. The results showed that the TN and TP removal rates ranged between 93.72%–95.82% and 92.73%–100%, respectively, under the five different strategies. The microalgal growth potential evaluated by the maximal growth rate (Rmax) was in the order of HMTC>HC>FC>AC>HATC. The values of biomass, total lipid yield, triacylglycerols (TAGs) yield, and total lipid content of the microalga cultivated in the last 5 d increased significantly, but the TAGs productivities of the five strategies were lower than those in the first 7 d. Compared with all the other cultivation strategies, the TAGs productivity and yield after 12 d of cultivation under the heterotrophic condition reached the highest values accompanying the highest level of intracellular reactive oxygen species (ROS), in which the TAGs yield reached 40.81 mg/L at the end of the cultivation period. The peaks in TAGs yield and ROS level suggested that HC was beneficial for lipids accumulation via regulating the cellular redox status and exerting ROS stress on microalgal cells. In summary, HMTC was the best cultivation strategy for improving the microalgal biomass and HC was the best strategy for microalgal TAGs accumulation to produce biodiesel.

Keywords： Chlorella sp. HQ     Cultivation strategy     lipids     Nitrogen removal     Phosphorus removal     Reactive oxygen species    

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<strong>Forward osmosis coupled with lime-soda ash softening for volume minimization of reverse osmosisconcentrate and CaCOstrong><strong>3strong><strong> recovery: A case study on the coalchemical industrystrong>

Jiandong Lu, Shijie You, Xiuheng Wang

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 1, doi: 10.1007/s11783-020-1301-6

Abstract: addition, CaCO3 (92.2% purity) was recovered from the softening sludge with an average yield of 5.6 kg/m3

Keywords： Coal chemical industry     Forward osmosis     Chemical softening     Reverse osmosis concentrate    

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<strong>Sugarcane bagasse amendment improves the quality of green waste vermicompost and the growth ofstrong><strong>Eisenia fetidastrong>

Linlin Cai, Xiangyang Sun, Dan Hao, Suyan Li, Xiaoqiang Gong, Hao Ding, Kefei Yu

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 4, doi: 10.1007/s11783-020-1240-2

Abstract: •Earthworms were able to convert green waste into more plant-available nutrients. •The part of heavy metals content increased in the compost added by earthworm. •The addition of SCB to GW did enhance earthworm biomass and humic acid content. •The resulting vermicomposts were characterized by neutral pH and lower EC value. Vermicomposting is a feasible method for disposing of lignocellulosic waste while generating a useful product. The current study assessed the potential of vermicomposting green waste mixed with sugarcane bagasse in proportions of 25%, 50%, and 75% (v:v, based on dry weight). The suitability was evaluated based on the agrochemical properties, earthworm biomass, and phytotoxicity. The final vermicomposts exhibited near-neutral pH values (7.1–7.6), and lower EC values (0.43–0.72 mS/cm) and C:N ratios (14.1–19.9).The content of available nutrients and CEC for all the vermicomposts exceeded those of the control compost (without earthworms). For vermicomposts, the average values of NO3–-N, AP, AK, and CEC were 53, 517, 1362 mg/kg, and 158 cmol/kg, respectively. The total contents of heavy metals increased in all vermicompost treatments compared to control composts with the following average final percentages: Zn (2.0%), Cr (15.5%), Pb (23.4%), and Cu (44.3%), but these amounts were safe for application in agroforestry. The addition of sugarcane bagasse to green waste significantly increased the content of total humic substance, humic acid and urease activity, acid and alkaline phosphatase activity, and Eiseniafetida reproduction. The addition of 25% sugarcane bagasse to green waste decreased the toxicity to germinating seeds. These results revealed that vermicomposting is a feasible way to degrade green waste into a value-added chemical product.

Keywords： Green waste     Earthworms     Sugarcane bagasse     Vermicomposting     Nutrient recovery    

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<strong>A fractional-order multifunctionalstrong><strong>nstrong><strong>-step honeycomb RLCcircuit networkstrong> Article

Ling ZHOU, Zhi-zhong TAN, Qing-hua ZHANG

Frontiers of Information Technology & Electronic Engineering 2017, Volume 18, Issue 8,   Pages 1186-1196 doi: 10.1631/FITEE.1601560

Abstract: We investigate a multifunctional -step honeycomb network which has not been studied before. By adjusting the circuit parameters, such a network can be transformed into several different networks with a variety of functions, such as a regular ladder network and a triangular network. We derive two new formulae for equivalent resistance in the resistor network and equivalent impedance in the LC network, which are in the fractional-order domain. First, we simplify the complex network into a simple equivalent model. Second, using Kirchhoff’s laws, we establish a fractional difference equation. Third, we construct an equivalent transformation method to obtain a general solution for the nonlinear differential equation. In practical applications, several interesting special results are obtained. In particular, an step impedance LC network is discussed and many new characteristics of complex impedance have been found.

Keywords： Honeycomb network     Equivalent transformation     Fractional differential equation     Impedance characteristics    

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<strong>H. sinensisstrong><strong> mycelium inhibits epithelial-mesenchymal transition by inactivatingthe midkine pathway in pulmonary fibrosisstrong>

Li Lu, Haiyan Zhu, Hailin Wang, Huaping Liang, Yayi Hou, Huan Dou

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 313-329 doi: 10.1007/s11684-020-0737-1

Abstract: The medical fungus has been used as a Chinese folk health supplement because of its immunomodulatory properties. Our previous studies established the antifibrotic action of mycelium (HSM) in the lung. The epithelial–mesenchymal transition (EMT) is involved in the pathogenesis of idiopathic pulmonary fibrosis. The present study investigates the role of HSM in mediating EMT during the development of pulmonary fibrosis. HSM significantly inhibits bleomycin (BLM)-induced pulmonary fibrosis by blocking the EMT. In addition, the expression levels of midkine are increased in the lungs of the BLM-induced group. Further analysis of the results indicates that the mRNA level of midkine correlated positively with EMT. HSM markedly abrogates the transforming growth factor β-induced EMT-like phenotype and behavior . The activation of midkine related signaling pathway is ameliorated following HSM treatment, whereas this extract also caused an effective attenuation of the induction of EMT (caused by midkine overexpression) . Results further confirm that oral medication of HSM disrupted the midkine pathway . Overall, findings suggest that the midkine pathway and the regulation of the EMT may be considered novel candidate therapeutic targets for the antifibrotic effects caused by HSM.

Keywords： epithelial−mesenchymal transition     H. sinensis mycelium     midkine     pulmonary fibrosis    

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NiFeRuO<strong>xstrong> nanosheets on Ni foam as an electrocatalyst for efficient

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11,   Pages 1698-1706 doi: 10.1007/s11705-023-2334-8

Abstract: The electrocatalyst NiFeRuOx/NF, comprised of NiFeRuOx nanosheets grown on Ni foam, was synthesized using a hydrothermal process followed by thermal annealing. NiFeRuOx/NF displays high electrocatalytic activity and stability for overall alkaline seawater splitting: 98 mV@ 10 mA∙cm−2 in hydrogen evolution reaction, 318 mV@ 50 mA∙cm−2 in oxygen evolution reaction, and a cell voltage of 1.53 V@ 10 mA∙cm−2, as well as 20 h of durability. A solar-driven system containing such a bifunctional NiFeRuOx/NF has an almost 100% Faradaic efficiency. The NiFeRuOx coating around Ni foam is an anti-corrosion layer and also a critical factor for enhancement of bifunctional performances.

Keywords： NiFeRuOx nanosheets     Ni foam     electrocatalysis     overall seawater splitting     solar-driven system    

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Features of seismic hazard in large dam projects and strong motion monitoring of large dams

Martin WIELAND,

Frontiers of Structural and Civil Engineering 2010, Volume 4, Issue 1,   Pages 56-64 doi: 10.1007/s11709-010-0005-6

Abstract: Among these dams were the 132-m-high Shapai RCC arch dam and the 156-m-high Zipingpu concrete face rockfillThese recently completed dams are dam types which, up to now, have not experienced strong ground shakingearthquake behaviors of the Sefid Rud, Zipingpu and Shapai dams, which, in the past, have experienced strongFinally, the need for strong motion instrumentation of large dams is discussed.dams located in areas of high seismicity, and dams showing signs of abnormal behavior be equipped with strong

Keywords： seismic hazard     arch dam     concrete face rockfill dam     strong motion instrumentation     reservoir-triggered    

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<strong>Erratum to: strong><strong>Past review, current progress, and challengesahead on thecocktail party problemstrong> Regular Papers

Yan-min QIAN, Chao WENG, Xuan-kai CHANG, Shuai WANG, Dong YU

Frontiers of Information Technology & Electronic Engineering 2019, Volume 20, Issue 3, doi: 10.1631/FITEE.19e0001

Abstract:

Keywords： None    

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Title Author Date Type Operation

Endothelial dysfunction in COVID-19 calls for immediate attention: the emerging roles of the endothelium in inflammation caused by SARS-CoV-2

Weijian Hang, Chen Chen, Xin A. Zhang, Dao Wen Wang

Journal Article

<strong>Mercury removal from aqueous solution using petal-like MoSstrong><strong>2strong><strong> nanosheetsstrong>

Ragini Pirarath, Palani Shivashanmugam, Asad Syed, Abdallah M.

Journal Article

<strong>FESEstrong><strong>’s Best Papers of 2017strong>

Journal Article

<strong>Photosynthesis and related metabolic mechanism of promoted rice (strong><strong>Oryza sativastrong><strong> L.) growth by TiOstrong><strong>2strong><strong> nanoparticlesstrong>

Yingdan Zhang, Na Liu, Wei Wang, Jianteng Sun, Lizhong Zhu

Journal Article

<strong>Adsorption characteristics of ciprofloxacin onto g-MoSstrong><strong>2strong><strong> coated biochar nanocompositesstrong>

Zhenyu Yang, Rong Xing, Wenjun Zhou, Lizhong Zhu

Journal Article

<strong>A newly defined dioxygenase system from strong><strong>Mycobacterium vanbaaleniistrong><strong> PYR-1 endowed with an enhanced activity of dihydroxylation of high-molecular-weight polyaromatichydrocarbonsstrong>

Yiquan Wu, Ying Xu, Ningyi Zhou

Journal Article

<strong>Fabrication and photocatalytic ability of an Au/TiOstrong><strong>2strong><strong>/reduced graphene oxide nanocompositestrong>

Fenghe Lv, Hua Wang, Zhangliang Li, Qi Zhang, Xuan Liu, Yan Su

Journal Article

<strong>Effects of cultivation strategies on the cultivation of strong><strong>Chlorellastrong><strong> sp.HQ in photoreactorsstrong>

Xiaoya Liu, Yu Hong, Peirui Liu, Jingjing Zhan, Ran Yan

Journal Article

<strong>Forward osmosis coupled with lime-soda ash softening for volume minimization of reverse osmosisconcentrate and CaCOstrong><strong>3strong><strong> recovery: A case study on the coalchemical industrystrong>

Jiandong Lu, Shijie You, Xiuheng Wang

Journal Article

<strong>Sugarcane bagasse amendment improves the quality of green waste vermicompost and the growth ofstrong><strong>Eisenia fetidastrong>

Linlin Cai, Xiangyang Sun, Dan Hao, Suyan Li, Xiaoqiang Gong, Hao Ding, Kefei Yu

Journal Article

<strong>A fractional-order multifunctionalstrong><strong>nstrong><strong>-step honeycomb RLCcircuit networkstrong>

Ling ZHOU, Zhi-zhong TAN, Qing-hua ZHANG

Journal Article

<strong>H. sinensisstrong><strong> mycelium inhibits epithelial-mesenchymal transition by inactivatingthe midkine pathway in pulmonary fibrosisstrong>

Li Lu, Haiyan Zhu, Hailin Wang, Huaping Liang, Yayi Hou, Huan Dou

Journal Article

NiFeRuO<strong>xstrong> nanosheets on Ni foam as an electrocatalyst for efficient

Journal Article

Features of seismic hazard in large dam projects and strong motion monitoring of large dams

Martin WIELAND,

Journal Article

<strong>Erratum to: strong><strong>Past review, current progress, and challengesahead on thecocktail party problemstrong>

Yan-min QIAN, Chao WENG, Xuan-kai CHANG, Shuai WANG, Dong YU

Journal Article